The correct base timing specification depends on the timing map in the bin file that you are using. If your bin is thinking that your base timing is set to 5* (as some of the VE OEM bins are set up) but you have it set to 15* (which is the factory setting for DEs and standard for Calum's bin files) then you will not get the expected results. So you have to make sure that you start your tuning at the base timing spec for the bin that you are running.
Then it makes sense to go to the dyno and adjust timing in 2* increments to get best results. If you have a programmable ECU, you can change advance in the timing map to optimize output depending on RPM (get the best timing for mid range and high RPM).
Generally, don't mess with timing until you confirm that you have a good safe AFR - otherwise your engine may be prone to detonation. With AFRs in the range of 12.8-13.0, NA SR20s generally stop giving more power with increased advance before they start to detonate. Get your best power and then back off a degree or two for safety.
Then it makes sense to go to the dyno and adjust timing in 2* increments to get best results. If you have a programmable ECU, you can change advance in the timing map to optimize output depending on RPM (get the best timing for mid range and high RPM).
Generally, don't mess with timing until you confirm that you have a good safe AFR - otherwise your engine may be prone to detonation. With AFRs in the range of 12.8-13.0, NA SR20s generally stop giving more power with increased advance before they start to detonate. Get your best power and then back off a degree or two for safety.