With money all things are possible.
I think you'd have serious problems mounting it, and even if you managed to get it working (you'd have to figure out how to fit the hub AND the QR where the splined connection is in the OEM wheel) it wouldn't look right.
What car is the S15 wheel in? If it's in the 98 SE-R in your sig, you'd also have all the airbag wiring and the clockspring to figure out. Not worth it IMO.
I think you'd have serious problems mounting it, and even if you managed to get it working (you'd have to figure out how to fit the hub AND the QR where the splined connection is in the OEM wheel) it wouldn't look right.
What car is the S15 wheel in? If it's in the 98 SE-R in your sig, you'd also have all the airbag wiring and the clockspring to figure out. Not worth it IMO.